Glove and stocking pattern

Half of people who have diabetes eventually develop diabetic peripheral neuropathy, and the warning signs are sensory symptoms that start in the distant periphery and progressing in a characteristic 'glove and stocking' way, glove and stocking pattern. People who have diabetes fear diabetic peripheral neuropathy DPNas it is common and the chance of developing this painful condition increases as disease duration increases. Half of glove and stocking pattern who have diabetes eventually develop DPN, and the warning signs are sensory symptoms that start in the distant periphery and progressing in a characteristic 'glove and stocking' way.

Many patients presenting themselves with complaints of numbness or weakness will eventually be shown to have a disorder of the peripheral nervous system. Although the differential diagnosis is large in these disorders, the combination of a directed neurologic history exam along with relatively simple ancillary testing will quickly narrow the differential diagnosis. As many of these disorders are treatable or curable, prompt recognition, especially early in the clinical course, is important. Peripheral neuropathies a. Many disease processes may preferentially attack either the axon or the myelin sheath of the peripheral nerve. As a rule, axonal peripheral neuropathies affect the longest axons first.

Glove and stocking pattern

Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet. It has a number of potential causes, including diabetes. Peripheral neuropathy is nerve damage to the peripheral nerves. These nerves send signals throughout the body and to the brain and spinal cord , also known as the central nervous system. Some types of peripheral neuropathy start in the hands and feet. Doctors call this stocking and glove distribution, as people may feel as though they are wearing stockings and gloves when they are not. This article explains what stocking glove neuropathy is, its symptoms, causes, and treatment options. It also lists some potential prevention methods. Stocking and glove distribution refers to a specific symptom people may experience with peripheral neuropathy. Peripheral neuropathy occurs due to damage to the motor, sensory, or autonomic nerves. Damage to the sensory nerves affects how people feel certain sensations, including touch and vibrations. Damage to the sensory nerves can affect the hands and feet in particular. People may feel as though they are wearing gloves and stockings when they are not, which is the reason for the term stocking and glove distribution. Sensory nerve damage can cause a loss of reflexes and coordination.

Treating the underlying cause may help resolve stocking glove neuropathy and prevent nerve damage from worsening. In these cases, a specialized test directed at autonomic functions, glove and stocking pattern, and other non-electrodiagnostic tests e. Nerve cells in the peripheral nervous system can keep growing, so they may recover and regenerate.

In the Western world, diabetes is the biggest cause of peripheral neuropathy, usually distal symmetric polyneuropathy but some times another polyneuropathy or a focal neuropathy. In addition, hypothyroidism and acromegaly can cause carpal tunnel syndrome and other sensory complaints. A complete blood cell count, nerve-conduction tests, thyroid-function tests needed in all patients with carpal tunnel syndrome , and when necessary, needle electromyography can help confirm the diagnosis. Treatment of underlying disease is the most successful management approach: Tight glucose control in diabetic patients, thyroid hormone replacement therapy in patients with hypothyroidism, and removal of the pituitary adenoma in patients with acromegaly are of proven benefit. Significant symptomatic relief of dysesthesias can be obtained with use of capsaicin cream, tricyclic antidepresants, anticonvulsant agents, or an antiarrhythmic drug. Abstract In the Western world, diabetes is the biggest cause of peripheral neuropathy, usually distal symmetric polyneuropathy but some times another polyneuropathy or a focal neuropathy. Publication types Review.

Peripheral neuropathy is one of the most common neurologic problems encountered by family physicians. It is important to differentiate peripheral neuropathy from other disorders with similar presentations and to identify and address potential causes. The pathophysiology of peripheral neuropathy results from injury to small- or large-diameter nerve fibers. Damage can occur to the cell body, axon, myelin sheath, or a combination of these, leading to symptoms such as numbness, tingling, pain, and weakness. Small nerve fibers mediate pain, temperature, and autonomic functions. A systematic approach should be used to evaluate and manage patients with symptoms of peripheral neuropathy Figure 1. CNS lesions should be suspected in patients with speech disturbance, ataxia, visual disturbance, cranial nerve involvement, or bowel and bladder incontinence. Evaluation for nerve compression, radiculopathy, or peripheral nerve root lesions should be considered in patients with symptoms that are asymmetrical; follow a dermatomal pattern; or are associated with numbness, imbalance, falls, ataxia, and paresthesias. If peripheral neuropathy is suspected, a differential diagnosis should be formulated through a history and physical examination.

Glove and stocking pattern

At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made. Stocking and glove neuropathy occurs when nerves in the arms and legs incur damage due to illness or disease. Stocking and glove neuropathy derives its name from the fact that the sensation often mimics the feeling of wearing gloves or stockings.

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Everyone can relate to falling asleep on their arm which initially causes numbness or lack of feeling negative symptom followed by intense pins and needles paresthesias positive symptom. What sensations can diabetic neuropathy cause? Lesions of the plexus are asymmetric with sensorimotor involvement of multiple nerves in one extremity. Of course, it is important to review any past medical history in a patient with a peripheral neuropathy. Preventive Care. Evaluation There are well over causes of peripheral neuropathy, including metabolic disorders, infections, vitamin deficiencies, toxic and drug-induced conditions, genetic abnormalities, inflammatory autoimmune conditions, dysproteinemias, and neoplasia. Treatment for stocking glove neuropathy may depend on the underlying cause and extent of nerve damage. Peripheral neuropathies a. Doctors call this stocking and glove distribution, as people may feel as though they are wearing stockings and gloves when they are not. The damage and clinical manifestations are usually located distally with a proximal progression. Sensory Large Fiber.

Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet.

Loss of sensation including vibration, proprioception, temperature, and pinprick sensations in distal extremities suggests peripheral neuropathy, as does a distal-to-proximal gradient of reflex elicitation. The damage and clinical manifestations are usually located distally with a proximal progression. Pes cavus is highly associated with inherited peripheral neuropathies. Peripheral neuropathies a. In more severe cases, sensory loss may be found over the anterior chest and abdomen, reflecting degeneration of the distal thoracic intercostal nerves. Large sensory fibers mediate vibration, proprioception and touch, whereas small sensory fibers convey pain and temperature sensations. EMG can detect active axonal damage, as evidenced by the presence of spontaneous muscle fiber activity at rest resulting from the absence of neuro-regulation denervation. The most common treatable causes are diabetes, hypothyroidism, and nutritional deficiencies. Several medical conditions are highly associated with peripheral neuropathy. Significant symptomatic relief of dysesthesias can be obtained with use of capsaicin cream, tricyclic antidepresants, anticonvulsant agents, or an antiarrhythmic drug. However, an occasional patient will be exposed to heavy metals or hexacarbons that result in their neuropathy.