Avidart

Do not pass avidart on to others, avidart. It may harm them, even if their symptoms are the same as yours. The active ingredient is dutasteride.

GlaxoSmithKline GSK announced today that it will no longer pursue global approval marketing authorisation for the use of Avodart dutasteride to reduce the risk of prostate cancer. This was essentially due toquestions regarding the clinical significance of reducing the risk of low grade prostate cancer, and uncertainties surrounding the possible explanations for the increased number of cases of high grade tumours in men treated with 5-alpha reductase inhibitors 5ARIs for prostate cancer risk reduction. Regulatory filings were also made in other countries outside the US and EU resulting in a small number of countries approving the indication. Overall, a combination of factors including the ongoing medical and scientific debate around the benefits and risks of 5ARIs for prostate cancer risk reduction, together with feedback from regulatory agencies has caused GSK to carefully consider its approach to the indication and subsequently withdraw ongoing applications for approval. GSK reviews the safety and performance of all its medicines on a continuous basis and is committed to further investigations to advance the understanding of the benefits and risks of dutasteride. To that end, dutasteride has been extensively studied in clinical trials involving 7, men with BPH and has an estimated 6.

Avidart

.

If you are allergic to peanut or soya, avidart, do not use this medicinal product. Contact your doctor or pharmacist avidart you have any questions about taking Avidart.

.

Note: Women of childbearing potential should not use or handle dutasteride capsules. Dutasteride can cause birth defects in male fetuses. Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems with urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely. Dutasteride blocks the action of an enzyme called 5-alpha-reductase. This enzyme changes testosterone to another hormone that causes the prostate to grow. As a result, the size of the prostate is decreased.

Avidart

This medication works by preventing the conversion of testosterone into dihydrotestosterone, blocking unnecessary hormonal processes that contribute to BPH. Avodart is approved by the FDA for use by men who have been diagnosed with an enlarged prostate. Because it affects sex hormones, Avodart is not safe for women or children to take or handle. It belongs to a class of medications called 5-alpha-reductase inhibitors 5ARIs that all work by blocking unnecessary hormonal processes in the body for certain men. These medicines work by suppressing a naturally-occurring enzyme in the liver called 5-alpha reductase. This enzyme is responsible for converting testosterone into dihydrotestosterone, a normal hormone that in some men can cause harmful hormonal abnormalities. DHT hormone contributes to medical and skin conditions like an enlarged prostate, acne, and baldness. Finasteride is another 5-alpha-reductase inhibitor commonly used to treat hair loss in men and enlarged prostate symptoms.

Lesbian siterip

Do not chew or break open the capsule. Keep taking Avidart for as long as your doctor tells you. N Engl J Med ; The active ingredient is: Dutasteride. Dutasteride has been found in the semen of men taking Avidart. This is a particular risk in the first 16 weeks of pregnancy. For further information please visit www. Swallow the capsules whole with water. The effect of Avidart on this serious form of prostate cancer is not clear. Overall, a combination of factors including the ongoing medical and scientific debate around the benefits and risks of 5ARIs for prostate cancer risk reduction, together with feedback from regulatory agencies has caused GSK to carefully consider its approach to the indication and subsequently withdraw ongoing applications for approval. GSK will also provide communications to physicians to facilitate awareness and understanding of any changes.

Dutasteride , sold under the brand name Avodart among others, is a medication primarily used to treat the symptoms of a benign prostatic hyperplasia BPH , an enlarged prostate not associated with cancer. A few months may be required before benefits occur.

This will reduce the risk of acute urinary retention and the need for surgery. Contact with the contents of the capsules may make your mouth or throat sore. GSK reviews the safety and performance of all its medicines on a continuous basis and is committed to further investigations to advance the understanding of the benefits and risks of dutasteride. Tell your doctor if you think any of these apply to you. N Engl J Med ; Possible side effects. Grunwaldzka Poznan, Poland. It may take up to 6 months or more for you to notice an effect. This could reduce your fertility. Dutasteride is absorbed through the skin and can affect the normal development of a male baby. In some situations surgery is necessary to remove or reduce the size of the prostate gland. If your partner is or may be pregnant, you must avoid exposing her to your semen. GlaxoSmithKline Pharmaceuticals S.