Why was ru58841 abandoned

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I started talking to some guys who said RU had some serious heart issues. Have any of your experienced this? I do not receive any compensation from any clinic. My comments are not medical advice. View my thread. Topical dutasteride journey.

Why was ru58841 abandoned

Topical anti-androgens seem to gain popularity within the last year or so. Topical dutasteride and finasteride have become staples in many hair loss sufferers' protocols. Many world-renowned hair transplant surgeons believe topical anti-androgens will become the gold standard in the future, which leaves many questioning where RU falls in efficacy and safety. In this article, we will be talking about RU as a treatment for hair loss and how it compares to other topical anti-androgens. RU RU is a nonsteroidal antiandrogen developed in the s by a French pharmaceutical company. Initially, the drug was named ProStrakan while it was under investigation for androgen-related conditions such as acne, genetic hair loss, and excessive hair growth. This makes the medication appealing to those who have suffered from side effects for inhibiting their DHT systemically. A study published in the Journal of Dermatology compared the efficacy between topical RU and oral finasteride. The researchers did not use human subjects but rather used bald monkeys, which should be noted because the results may vary with humans. The researchers placed the monkeys in different groups the placebo, finasteride, and RU groups. The researchers tested the levels of serum DHT within the monkey's body.

The issue is I don't speak French, and they may not speak english. This recovery may be so effective that hair growth becomes stronger than before in individuals using the treatment.

We send out discount codes periodically to our subscribers. Jan 8, Hair loss can be a concern for many, and in the quest for solutions, RU has piqued the interest of those looking for effective remedies. With the buzz around this compound on the rise, there's a clear need for accurate information. In this post, we will try to provide straightforward answers to the common questions people have about RU , being a reliable resource for those seeking clarity on its uses and effects. RU is a substance that scientists developed in the early s, originally aiming to treat prostate cancer by applying it on the skin. However, after initial trials showed no effect on the prostate, it was abandoned for cancer treatment.

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Why was ru58841 abandoned

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There are plenty of studies showing that topical finasteride is almost as effective as the oral version. If left untreated, it can lead to permanent scarring of the lungs, such that you can no longer breath and can possibly die. Thanks for this post James, as i use RU at the moment i am in concern of side effects. Remember Me? However, it's important to be aware that using Minoxidil topically may lead to more side effects, both the general ones it's known for and an increased chance of androgenic side effects. Research and Development Originally developed as a potential treatment for androgenetic alopecia, RU has undergone various studies to assess its effectiveness and safety. Posted November 4, edited. It may not display this or other websites correctly. Last Post By bigsprotina. This results in shorter, thinner, and weaker hair. Consider baseline pulmonary function tests.

RegenRX, a company based in Tucson, AZ, has revealed that men and women may be able to get back the hair of their youth by using RU, which has been clinically proven to move the hair from the telogen phase or dormant phase to the anagen phase or growth phase. This may allow dormant hair follicles to become active again.

However, the odd thing is that the results of this study were never published, but a second phase trial still went through. Hopefully, there will be more information out on these two treatments soon. Hair Growth Cycle Alteration: The altered gene function affects the hair growth cycle, specifically lengthening the anagen phase the hair loss phase. By blocking the DHT pathway, RU aims to halt this miniaturization process, allowing hair follicles to remain active and produce healthier, thicker hair. Check this out, some guy claims to have actually gotten through to one of the researchers and was apparently able to ask a few questions regarding RU:. Log in Register. Some people have DM'd me about potentially contacting responsible doctor's and facilities where these trials took place. They may have just assumed it wasn't worth it if it didn't beat the efficacy of existing treatments. You are using an out of date browser. Applied directly to the scalp, it's widely accessible but requires consistent use for sustained effects. I think the CEO said after phase 2, and before the drug was abandoned, that it outperformed fin at 6 months, and I personally believe it was probably just too similar or maybe even less effective than finasteride and so it was deemed to be unprofitable, or something along those lines anyway rather than because it was unsafe. RU is classified as an anti-androgen, which means it hinders the effects of androgens, particularly dihydrotestosterone DHT.