Wellbutrin and jaw clenching

Federal government websites often end in. The site is secure. Antidepressant-associated movement disorders are a well-described phenomenon. However, antidepressant-associated bruxism, jaw pain, or jaw spasm, while reported in dental literature, is less commonly recognized among neurologists.

Why do SSRIs cause jaw clenching? While the exact mechanism is unknown, it appears that SSRIs trigger jaw clenching because of their effect on the level of neurotransmitters like serotonin in the brain. These neurotransmitters control mood, but they also contribute to movement regulation. Recent clinical evidence points to a significant association between selective serotonin reuptake inhibitor SSRI antidepressant drugs and jaw clenching. The effect is not permanent, as SSRI jaw clenching starts around 3 weeks after starting the medication and resolves 3 weeks after stopping. In a article in the journal BMC Psychiatry, researchers found that compared to all other medications, your chances of reporting bruxism when taking antidepressants are 10 times higher than they are with any other type of medication.

Wellbutrin and jaw clenching

Certain medications and drugs act on the brain by stimulating it. The results suggest brain stimulation is believed to contribute to grinding. Scientific data shows several neurotransmitters are involved in the effect of various drugs on bruxism. The dopaminergic systems in the striated body and the frontal lobe of the brain are of special importance, since hyperactivity generates bruxism, particularly the mandibular movement with tooth grinding. Selective Serotonin Reuptake Inhibitors SSRIs — Prescribed for depression, obsessive-compulsive disorder, anxiety, panic disorder, post-traumatic stress disorder, seasonal affective disorder, and depressive episodes of bipolar disorder, social phobia, premenstrual dysphoric disorder and menopause. In some reported cases where bruxism is thought to be initiated by SSRIs, decreasing the dosage may resolve the issue. Other sources state reports of SSRIs causing bruxism are rare and it only happens with long-term use. Dextroamphetemine Sulf-Saccharate — Prescribed for concentration, focus and fidgeting. Bruxism: The Grind of the Matter. Course Number:

The two related classes of antidepressants with the strongest association with clenching were the SSRIs and the serotonin-norepinephrine reuptake inhibitors SNRIs.

We are incredibly fortunate to live in a time when some of our most painful and debilitating medical conditions can be well-controlled with prescription medications, allowing us to enjoy a more pleasurable quality of life. Jaw pain is a common complication that many people experience as the result of taking certain prescription medications for the treatment of other health conditions. Technically known as TMJ disorder, clenching and gritting the teeth can sometimes be triggered by the medications that are used to treat:. A number of medications that are used to treat these conditions can also trigger jaw problems, including:. These medications have been shown to lead to the unconscious habit of clenching or grinding the teeth, especially at night. Unfortunately, this destructive behavior causes headaches, tooth sensitivity , broken enamel, damaged dental work, earaches, and tongue-biting.

Our pharmacist answers the latest question regarding what to do if your SSRI causes jaw clenching. I'm on citalopram 40mgs daily, bupropion sr mgs daily, hydroxyzine 25mgs 3x daily, trazodone mgs nightly. Can any of one of these medications be a side affect causing my jaw to lock up. If so which one. My dentist said I only open 20 centimeters and it is not a dental issue. While not common, jaw clenching, grinding of teeth and a general condition known as bruxism CAN be caused by some of the medications you are taking including citalopram, trazodone and Wellbutrin.

Wellbutrin and jaw clenching

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention.

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Unfortunately, this destructive behavior causes headaches, tooth sensitivity , broken enamel, damaged dental work, earaches, and tongue-biting. A total of 11 beneficial interventions were reported. This phenomenon may be seen in a variety of serotonergic antidepressants, and may be most associated with fluoxetine, sertraline, or venlafaxine. All rights reserved. We also include a discussion of epidemiology and proposed pathophysiology of this phenomenon. J Psychopharmacol Oxf Engl ; 24 — She described her symptoms as an achy, persistent right-sided pain, worse in the morning. Acta Reumatol Port ; 40 — The case of spontaneous symptom resolution without intervention, as mentioned, reported resolution after 4 weeks. Patients who experience this condition may benefit from the addition of buspirone 5 and 10 mg in daily, twice daily, or 3 times daily dosing; dose reduction and antidepressant cessation may also be considered. While the exact mechanism is unknown, it appears that SSRIs trigger jaw clenching because of their effect on the level of neurotransmitters like serotonin in the brain. Brain MRI obtained prior to her referral to neurology was unremarkable. We recorded demographic information, psychiatric diagnoses, time to symptom onset, offending agents, interventions, and time to symptom resolution for inclusion in our systematic review.

Temporomandibular joint disorder TMD is a broad pain disorder that refers to several conditions affecting the temporomandibular joint of the jaw and the muscles of mastication. As with most pain disorders, a high prevalence of depression and anxiety is associated with TMD. Research has shown that selective serotonin reuptake inhibitors SSRIs , the first-line drug therapy for major depressive disorder, may not be suitable for TMD patients because SSRIs can induce teeth-grinding, otherwise known as bruxism.

Successful monitoring of fluoxetine-induced nocturnal bruxism: a case report. The causes of bruxism are poorly understood, and often related to emotional stress. Bruxism possibly induced by venlafaxine. Case summary: A year-old white man with a history of chronic low-back pain and tension headaches, taking no other medications, was started on bupropion SR mg once a day for depression. Table 2 Patient data. Despite the notion of bruxism being a behavioral phenomenon, there are several case reports and series describing a possible relationship between bruxism and serotonergic antidepressants, including selective serotonin reuptake inhibitors SSRIs and serotonin—norepinephrine reuptake inhibitors SNRIs. Soyata AZ, Oflaz S. Next, talk to the dentist to find out if a night guard or occlusal guard can provide the necessary protection as long as you are taking the medication. J ECT ; 19 — These symptoms need to be taken seriously because acute jaw pain, if untreated, is a major risk factor for developing a chronic TMJ disorder, according to a report by the National Academy of Sciences. Interestingly, aripiprazole is also a 5HT 1A partial agonist throughout the brain, and may work through a similar mechanism to alleviate antidepressant-associated bruxism. J Clin Psychiatry ; 54 — Indian J Psychol Med ; 37 — More Articles.