Methylenedioxymethamphetamine
MDMA 3,4-methylenedioxymethamphetamine is similar to an amphetamine Amphetamines Amphetamines are stimulant drugs that are methylenedioxymethamphetamine to treat methylenedioxymethamphetamine medical conditions but are also subject to abuse. Amphetamines increase alertness, enhance physical performance, methylenedioxymethamphetamine, and produce euphoria See also Amphetamines Amphetamines Amphetamines are stimulant drugs that are used to treat certain medical conditions but are also subject to abuse, methylenedioxymethamphetamine.
MDMA 3,4-methylenedioxymethamphetamine is an amphetamine analog with stimulant and hallucinogenic effects. MDMA acts primarily on neurons that produce and release serotonin, but it also affects dopaminergic neurons. MDMA is usually taken as a pill; effects begin 30 to 60 minutes after ingestion and typically last 4 to 6 hours. MDMA is often used at dance clubs, concerts, and rave parties. See also Amphetamines Amphetamines Amphetamines are sympathomimetic drugs with central nervous system stimulant and euphoriant properties whose toxic adverse effects include delirium, hypertension, seizures, and hyperthermia MDMA causes a state of excitement and disinhibition and accentuates physical sensation, empathy, and feelings of interpersonal closeness. Toxic effects are similar to those of the other amphetamines but are less common, perhaps because use is more likely to be intermittent.
Methylenedioxymethamphetamine
Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Rick Figurasin ; Vincent R. Lee ; Nicole J. Authors Rick Figurasin 1 ; Vincent R. Lee 2 ; Nicole J. Maguire 3. MDMA, or 3,4-methylenedioxymethamphetamine, is a synthetic amphetamine derivative known as a recreational drug since the s by street names like "Ecstasy," "Molly," and "XTC.
Serotonin depletion following MDMA use can cause depression in subsequent days. Expert Review of Clinical Pharmacology. Neuroscience Lettersmethylenedioxymethamphetamine
Short-term adverse effects include grinding of the teeth , blurred vision , sweating and a rapid heartbeat , [21] and extended use can also lead to addiction , memory problems , paranoia and difficulty sleeping. Deaths have been reported due to increased body temperature and dehydration. Following use, people often feel depressed and tired , although this effect does not appear in clinical use, suggesting that it is not a direct result of MDMA administration. MDMA has limited approved medical uses in a small number of countries, [31] but is illegal in most jurisdictions. In general, MDMA users report feeling the onset of subjective effects within 30 to 60 minutes of oral consumption and reaching peak effect at 75 to minutes, which then plateaus for about 3. The experience elicited by MDMA depends on the dose, setting, and user. For example, MDMA used at parties is associated with high motor activity, reduced sense of identity, and poor awareness of surroundings.
MDMA 3,4-methylenedioxymethamphetamine is similar to an amphetamine Amphetamines Amphetamines are stimulant drugs that are used to treat certain medical conditions but are also subject to abuse. Amphetamines increase alertness, enhance physical performance, and produce euphoria See also Amphetamines Amphetamines Amphetamines are stimulant drugs that are used to treat certain medical conditions but are also subject to abuse. MDMA causes excitement and disinhibition a loosening of control over behaviors. It also accentuates physical sensation, empathy, and feelings of interpersonal closeness. Toxic effects are similar to those of the other amphetamines but are less common, perhaps because people are more likely to use MDMA intermittently. However, even with casual use, significant problems such as hyperthermia Serotonin Syndrome Serotonin syndrome is a potentially life-threatening drug reaction that tends to cause high body temperature, muscle spasms, and anxiety or delirium. Serotonin is a chemical that transmits impulses
Methylenedioxymethamphetamine
MDMA is a synthetic drug that acts as a stimulant and hallucinogen. It has also been described as an entactogen—a drug that can increase self-awareness and empathy. Ecstasy is often used to refer to MDMA in the tablet or capsule form, which is the most common way people take the drug. Adulterants found in ecstasy tablets purchased on the street have included methamphetamine, the anesthetic ketamine, caffeine, the diet drug ephedrine, 20 the over-the-counter cough suppressant dextromethorphan, 21,22 heroin, phencyclidine PCP , and cocaine.
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Yes No. Retrieved 2 December For example, MDMA used at parties is associated with high motor activity, reduced sense of identity, and poor awareness of surroundings. Agonists: 4-Methylaminorex Aminorex Amphetamines e. Retrieved 8 October Substituted amphetamine Sub. Neuropharmacology 29 , — The characteristic hallucinations produced by compounds like LSD and mescaline typically disrupted interrogation sessions. Neurosci 11 , — Kaiserliches Patentamt. Drug Enforcement Agency, U.
MDMA affects the brain by increasing the activity of at least three neurotransmitters the chemical messengers of brain cells : serotonin, 89,90 dopamine, and norepinephrine. MDMA causes greater release of serotonin and norepinephrine than of dopamine.
The neurotoxic effects of MDMA have been extensively reviewed by others, , , , , , , and thus, we will focus only on the key studies. It also accentuates physical sensation, empathy, and feelings of interpersonal closeness. MDMA is mainly available in colorful tablets with logo brands but may also be in capsule, powder, and liquid forms. Oxford American Handbook of Critical Care. Neurotoxicology and Teratology. EU Drug Market: Heroin and other opioids. Rev 42 ,— MDMA causes a state of excitement and disinhibition and accentuates physical sensation, empathy, and feelings of interpersonal closeness. Retrieved 31 August Like most psychostimulants, MDMA causes robust changes in gene expression and protein levels associated with neural plasticity. Continuing Education Activity MDMA, or 3,4-methylenedioxymethamphetamine, is a synthetic amphetamine derivative known as a recreational drug since the s by street names like "Ecstasy," "Molly," and "XTC. Justia Law. Drugsite Trust.
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