Expassy

Protein identification and analysis software performs a central role in the investigation expassy proteins from two-dimensional 2-D gels and mass spectrometry.

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Expassy

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors. It has now evolved, becoming an extensible and integrative portal accessing many scientific resources, databases and software tools in different areas of life sciences. Specifically, a single web portal provides a common entry point to a wide range of resources developed and operated by different SIB groups and external institutions. Additionally, the availability and usage of resources are monitored. The portal is aimed for both expert users and people who are not familiar with a specific domain in life sciences. The new web interface provides, in particular, visual guidance for newcomers to ExPASy. We have now turned it into a bioinformatics resource portal that serves not only the field of proteomics but also other domains of life sciences. The major changes and their rationale are described below:. However, in the last decade, the SIB has grown to a Swiss-wide institute that covers all major bioinformatics domains, including proteomics, genomics, transcriptomics, evolution, systems biology, etc. One goal of the new ExPASy portal is to serve as entry point to all scientific databases and tools provided by the SIB, and we revisited the original focus on proteomics accordingly;. With the inclusion of resources from more than 20 groups in five different cities Geneva, Lausanne, Berne, Basel and Zurich , located at seven Swiss higher education institutions, ExPASy has been turned into a federated portal that provides access to resources at different locations. Each resource is maintained independently but many of them still follow a common release cycle or database update schedule. Keeping independent release cycles for some resources allows more flexibility for the individual resource providers;. This relies on a standardized search interface that permits querying several different resources in parallel;. We have added an attractive visual interface that is addressed to new users even if they have little experience with the provided domains and technologies; and.

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Federal government websites often end in. The site is secure. It provides access to a variety of databases and analytical tools dedicated to proteins and proteomics. Analysis tools are available for specific tasks relevant to proteomics, similarity searches, pattern and profile searches, post-translational modification prediction, topology prediction, primary, secondary and tertiary structure analysis and sequence alignment. These databases and tools are tightly interlinked: a special emphasis is placed on integration of database entries with related resources developed at the SIB and elsewhere, and the proteomics tools have been designed to read the annotations in SWISS-PROT in order to enhance their predictions. In addition to the main site in Switzerland, seven mirror sites in different continents currently serve the user community. One of the SIB's windows to the world is the ExPASy server, which focuses on proteins and proteomics, and provides access to a variety of databases and analysis tools.

Federal government websites often end in. The site is secure. It provides access to a variety of databases and analytical tools dedicated to proteins and proteomics. Analysis tools are available for specific tasks relevant to proteomics, similarity searches, pattern and profile searches, post-translational modification prediction, topology prediction, primary, secondary and tertiary structure analysis and sequence alignment. These databases and tools are tightly interlinked: a special emphasis is placed on integration of database entries with related resources developed at the SIB and elsewhere, and the proteomics tools have been designed to read the annotations in SWISS-PROT in order to enhance their predictions. In addition to the main site in Switzerland, seven mirror sites in different continents currently serve the user community. One of the SIB's windows to the world is the ExPASy server, which focuses on proteins and proteomics, and provides access to a variety of databases and analysis tools.

Expassy

Federal government websites often end in. The site is secure. It has now evolved, becoming an extensible and integrative portal accessing many scientific resources, databases and software tools in different areas of life sciences. Specifically, a single web portal provides a common entry point to a wide range of resources developed and operated by different SIB groups and external institutions. Additionally, the availability and usage of resources are monitored. The portal is aimed for both expert users and people who are not familiar with a specific domain in life sciences. The new web interface provides, in particular, visual guidance for newcomers to ExPASy. We have now turned it into a bioinformatics resource portal that serves not only the field of proteomics but also other domains of life sciences. The major changes and their rationale are described below:.

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Wilkins M. Altschul S. Rights and permissions Reprints and permissions. Drug design. We hope that in the next years we will be able to add many new features to those that are already available. Google Scholar Crossref. Manual: Accessible Real time : Checking Google Scholar Wilkins, M. Dinucleotide Weight Tensor toolbox and visualisation service. Guex N.

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Typically, we ask users to specify the resource for which they have a specific question, i. Search ADS. PeptideCutter predicts potential protease cleavage sites and sites cleaved by chemicals in a given protein sequence. Detailed information describing a resource. Dmitry Kuznetsov. Funding for open access charge: SIB. In , Expasy was redesigned through a user-centric approach, known as User-Centred Design UCD , whose aim is to create user interfaces that are easy-to-use, efficient and targeting the intended community. Publisher Name : Humana Press. Article Google Scholar Gasteiger, E. Print ISBN : Biotechnology , 13 , —