Catechol

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Catechol, also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound essentially used as building block. It is available in two forms: F lakes solid form and Molten liquid form. Catechol offers multiple possibilities of bondings, providing different type of interactions and related properties:. First industrialized in the s by Syensqo Food Experts, ethylvanillin provides a warm and powerful vanilla note. Discover Syensqo best in class technology available for fire safety in textiles and garments: flame retardant protection for lifetime of the garment, strict quality procedures and extremely comfortable for wearers in Industrial and Personal environments. Absolutely no carbon of petrochemical origin is used in its production.

Catechol

It is the ortho isomer of the three isomeric benzenediols. This colorless compound occurs naturally in trace amounts. It was first discovered by destructive distillation of the plant extract catechin. About 20, tonnes of catechol are now synthetically produced annually as a commodity organic chemical, mainly as a precursor to pesticides, flavors, and fragrances. Catechol was first isolated in by Edgar Hugo Emil Reinsch — by distilling it from the solid tannic preparation catechin , which is the residuum of catechu , the boiled or concentrated juice of Mimosa catechu Acacia catechu. This was a thermal decomposition product of the flavanols in catechin. In , both Wackenroder and Zwenger independently rediscovered catechol; in reporting on their findings, Philosophical Magazine coined the name pyrocatechin. Catechol has since been shown to occur in free form naturally in kino and in beechwood tar. Its sulfonic acid has been detected in the urine of horses and humans. Catechol is produced industrially by the hydroxylation of phenol using hydrogen peroxide. It can be produced by reaction of salicylaldehyde with base and hydrogen peroxide Dakin oxidation , [10] as well as the hydrolysis of 2-substituted phenols, especially 2-chlorophenol , with hot aqueous solutions containing alkali metal hydroxides.

Addition of 0. Catechol alone induced no neoplasms, but increased the incidence of forestomach hyperplasia compared with that in unexposed rats. Related content.

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Federal government websites often end in. The site is secure. Preview improvements coming to the PMC website in October Learn More or Try it out now. Catechol is a key constituent in mussel adhesive proteins and is responsible for strong adhesive property and crosslinking formation. Plant-based polyphenols are also capable of chemical interactions similar to those of catechol and are inherently antimicrobial. This review reports a series of catechol-based antimicrobial polymers classified according to their antimicrobial mechanisms. Catechol is utilized as a surface anchoring group for adhering monomers and polymers of known antimicrobial properties onto various types of surfaces. During catechol oxidation, reactive oxygen species ROS is generated as a byproduct, and the use of the generated ROS for antimicrobial applications was also introduced.

Catechol

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'catechol. Send us feedback about these examples. Accessed 19 Mar. Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! See Definitions and Examples ». Log In.

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An evaluation of the E. EC Number. A control group was given the multiple initiation treatments only. After application to mice, catechol was negative in one and positive in three studies of micronucleus formation in bone marrow. PLOS Pathog. Clear Turn Off Turn On. Chapman D. No international guideline for catechol in drinking-water has been established WHO, Effect of phenol and catechol on the kinetics of human myeloperoxidase-dependent hydroquinone metabolism. Chemical and physical data 1. These guar-based polymers answer the need for clean ingredients in personal care cosmetics. Article Talk. Van Duuren B.

Federal government websites often end in.

The major metabolic pathways in experimental animals are sulfation and glucuronidation. Phorbol myristate acetate and catechol as skin cocarcinogens in Sencar mice. Signal word. Thermoplastic additives that imparts unique benefits to polymer resins, such as the elimination of melt fracture and the reduction of die buildup. Animal carcinogenicity data Catechol was tested for carcinogenicity by oral administration in one study in mice and in two studies in rats. These guar-based polymers answer the need for clean ingredients in personal care cosmetics. These phenols phenol, catechol and hydroquinone may play a role in benzene toxicity to bone marrow: all three are formed as benzene metabolites Smith et al. The CCGG sites but not CGCG sites of the Pg1 gene showed slightly increased methylation frequency in adenomatous tissues, while the methylation pattern of the Pg1 gene was not significantly different from that of normal tissue in the Pg1-altered foci Tatematsu et al. It was noted previously that skin contact with catechol causes dermatitis, and absorption through the skin may give rise to symptoms similar to those seen in phenol poisoning IARC, Lewis, R. PMID Benzene-1,2-diol [1]. Pyrocatechol [1] 1,2-Benzenediol 2-Hydroxyphenol 1,2-Dihydroxybenzene o -Benzenediol o -Dihydroxybenzene.