Adriamycin

Doxorubicin injection is used together with other medicines to treat cancer of the blood, lymph system, bladder, breast, stomach, lungs, ovaries, adriamycin, nerves, kidneys, adriamycin, bones, and soft tissues, including muscles and tendons. It may also be used to treat adriamycin kinds of cancer, as determined by your doctor.

For the best browsing experience please enable JavaScript. Instructions for Microsoft Edge and Internet Explorer , other browsers. It is a treatment for a number of different cancer types. You might have doxorubicin in combination with other cancer drugs. Doxorubicin is a type of chemotherapy drug called an anthracycline. It slows or stops the growth of cancer cells by blocking an enzyme called topo isomerase 2.

Adriamycin

Federal government websites often end in. The site is secure. Adriamycin doxorubicin hydrochloride is an antineoplastic agent effective against a wide range of malignant conditions, although cardiac toxicity, especially dose-dependent cardiomyopathy, limits its long-term use. Previous mediastinal radiation therapy or left ventricular dysfunction and advanced age increase the risk of this complication developing. Unfortunately, there is no readily available, noninvasive method that can predict Adriamycin-induced congestive heart failure CHF. However, both endomyocardial biopsy and radionuclide ejection-fraction measurement are promising techniques which may soon permit selection of patients who can safely receive this drug. At present, Adriamycin-induced CHF can best be prevented by limiting the total dose as follows: to mg per sq meter following mediastinal radiation and to mg per sq meter for patients without other significant risk factors. Consideration of dose-response data and use of a weekly schedule may soon permit the administration of Adriamycin for long-term antineoplasm therapy. Full text is available as a scanned copy of the original print version. Get a printable copy PDF file of the complete article K , or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed.

A single copy of these materials may be reprinted for noncommercial personal use only. Following administration of this form of doxorubicin, small amounts of the drug can leak from capillaries in the palms of the adriamycin and soles of the feet, adriamycin.

Doxorubicin , sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. Common side effects include hair loss , bone marrow suppression , vomiting , rash, and inflammation of the mouth. Doxorubicin was approved for medical use in the United States in It is indicated to treat multiple myeloma in combination with bortezomib. Doxorubicin is commonly used to treat some leukemias and lymphomas , as well as cancers of the bladder , breast , stomach , lung , ovaries , thyroid , soft tissue sarcoma , multiple myeloma , and others.

Official websites use. Share sensitive information only on official, secure websites. Doxorubicin should be administered only into a vein. However, it may leak into surrounding tissue causing severe irritation or damage. Your doctor or nurse will monitor your administration site for this reaction. If you experience any of the following symptoms, call your doctor immediately: pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected. Doxorubicin may cause serious or life-threatening heart problems at any time during your treatment or months to years after your treatment has ended.

Adriamycin

Doxorubicin is used to treat different types of cancers that affect the breast, bladder, kidneys, ovaries, thyroid, stomach, lungs, bones, nerve tissues, joints, and soft tissues. Doxorubicin is also used to treat Hodgkin lymphoma, non-Hodgkin lymphoma, and certain types of leukemia. Doxorubicin may also be used for purposes not listed in this medication guide. You should not use this medicine if you are allergic to doxorubicin or similar medications doxorubicin, daunorubicin, epirubicin, idarubicin, mitoxantrone , or if you have:. Tell your doctor about all other cancer medicines or radiation treatments you have received in the past. Using doxorubicin may increase your risk of developing a bone marrow disease or other types of leukemia later in life. Ask your doctor about your specific risk. You may need to have a negative pregnancy test before starting this treatment. Both men and women using this medicine should use effective birth control to prevent pregnancy. Doxorubicin can harm an unborn baby or cause birth defects if the mother or father is using this medicine.

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Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. Use an effective form of birth control to keep you or your partner from getting pregnant during therapy and for 6 months after the last dose of this medicine. Doxorubicin and several chemotherapeutic drugs including cyclophosphamide can cause a loss of skin pigmentation. ISBN This won't harm you. Tell your healthcare team about any medicines you are taking. Doxorubicin cardiomyopathy: evaluation by phonocardiography, endomyocardial biopsy, and cardiac catheterization. Survey on the vitamin aspects of coenzyme Q. Archived from the original PDF on 21 September

Doxorubicin injection is used together with other medicines to treat cancer of the blood, lymph system, bladder, breast, stomach, lungs, ovaries, thyroid, nerves, kidneys, bones, and soft tissues, including muscles and tendons.

Published phase II study results have shown that Myocet, trastuzumab, and paclitaxel can safely be used concurrently without the cardiac risk, as measured by reduction in LVEF function, while still achieving superior tumor response. Painkillers and mouth washes can help to reduce the soreness and keep your mouth healthy. Archived from the original on 21 June Doxorubicin can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. Do not get close to them, and do not stay in the same room with them for very long. If this isn't possible, wash your hands well after changing their nappy. This includes vitamins, herbal supplements and over the counter remedies. Sometimes, doxorubicin may be given directly into the bladder to treat cancer of the bladder lining. You have heart tests to check how well your heart is working before you start treatment. Since the growth of normal body cells may also be affected by doxorubicin, other effects will also occur. Substitution would be desirable because liposome-encapsulated doxorubicin is less cardiotoxic than unencapsulated doxorubicin. ISBN Retrieved 28 June You might have other symptoms depending on where the infection is.